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Supervised by Ministry of Industry and Information Technology of The People's Republic of China Sponsored by Harbin Institute of Technology Editor-in-chief Yu Zhou ISSNISSN 1005-9113 CNCN 23-1378/T

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Related citation:TANG Hao-xuan,Qu Yi.Application of ACO algorithm in protein structure prediction[J].Journal of Harbin Institute Of Technology(New Series),2009,16(1):111-114.DOI:10.11916/j.issn.1005-9113.2009.01.023.
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Application of ACO algorithm in protein structure prediction
Author NameAffiliation
TANG Hao-xuan School of Computer Science and Technology, Harbin Institute of Technology,Harbin 150001,China 
Qu Yi School of Computer Science and Technology, Harbin Institute of Technology,Harbin 150001,China 
Abstract:
The hydrophobic-polar (HP) lattice model is an important simplified model for studying protein folding. In this paper, we present an improved ACO algorithm for the protein structure prediction. In the algorithm, the "lone"ethod is applied to deal with the infeasible structures, and the "oint mutation and reconstruction"ethod is applied in local search phase. The empirical results show that the presented method is feasible and effective to solve the problem of protein structure prediction, and notable improvements in CPU time are obtained.
Key words:  protein structure prediction  HP lattice model  ACO algorithm
DOI：10.11916/j.issn.1005-9113.2009.01.023
Clc Number:TP301.6
Fund:

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