| Author Name | Affiliation | Postcode | | Ding Yanan | 1. School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150080, China
2. MOE Key Lab of Micro-System and Micro-Structures Manufacturing, Harbin Institute of Technology, Harbin 150080, China
3. State Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150080, China | 150081 | | Xiao Haiying* | School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150080, China | 150081 | | Hu Pingan | 1. School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150080, China
2. MOE Key Lab of Micro-System and Micro-Structures Manufacturing, Harbin Institute of Technology, Harbin 150080, China
3. State Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150080, China
4. School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150080, China | 150081 |
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| Abstract: |
| Advanced in wireless technologies and flexible materials with great biocompatibility, wearable devices have been utilized in the field of healthcare, sports management, and diseases prevention, which have been widely applied in current electronic equipment. Sweat, as a common metabolite on the skin surface, contains a wealth of biomarkers for disease detection and diagnosis. Therefore, developing wearable sweat sensors can provide a non-invasive method for health data collecting, sports monitoring, and clinical diagnosis in a convenient way. Recent research in sweat metabolomics has offered a lot of information for sweat analysis and the wearable sweat sensors with small size, various sensing, and transmission units, and good skin contact has exhibited dynamic multi-signal detection. This article introduces the biomarkers in sweat related to different diseases and the current development of sweat sensors for user’s activation monitoring and diseases detection. The barriers and difficulties in the future are also discussed and perspectives in the next generation sweat sensors are proposed. |
| Key words: Sweat sensor, Sweat metabolites, Disease monitoring, Wearable device |
| DOI： |
| Clc Number:O69 |
| Fund: |
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| Descriptions in Chinese: |
| 随着无线技术和高生物相容性柔性材料的发展，可穿戴设备在医疗保健、运动管理和疾病预防等领域展现出许多潜力，广泛应用于现在的电子设备中。汗液作为皮肤表面的常见代谢物，含有丰富的用于疾病检测和诊断的生物标志物。因此，开发可穿戴汗液传感器可以方便健康数据的采集、运动的监测，并为疾病的临床诊断提供一种便捷的非侵入性方法。最近的汗液代谢组学的研究为汗液分析提供了大量信息。目前的汗液传感器具有体积小、多种传感单元、皮肤接触良好的优点，可以实现多信号的动态检测。本文介绍了汗液中与不同疾病相关的生物标志物，以及汗液传感器在用户活动监测和疾病检测方面的发展现状。我们还讨论了未来的障碍和困难，并对未来新一代汗液传感器进行了展望。 |
