| Security evaluation of compounded microbial flocculant |
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| 作者姓名： | 马放 王博 范春 杨基先 李百祥 刘艳滨 |
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| 作者单位： | [1]SchoolofMunicipalandEnvironmentalEngineering,HarbinInstituteofTechnology,Harbin150090,China [2]HarbinMedicalUniversity,Harbin150001,China |
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| 基金项目： | SupportedbytheScienceFoundationofHeilongjiangProvince(GrantNo .GB0 2C2 0 2 -0 2 )andtheScienceFoundationofHeilongjiangProvinceforYouth(Grant
No .QC0 1C0 4) . |
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| 摘 要： | A new kind of compounded microbial flocculant (CMBF) for water and wastewater treatment has been developed through biological technology. In order to discuss its biological security, four groups of experiments, rat acute toxicity test via mouth, salmonella assay in vitro, mouse micronucleus in vivo test and teratogenesis test were conducted to evaluate its general toxicity, genotoxicity and generative toxicity. The experimental results showed that this type of compounded microbial flocculant was a substantial non-toxic substance based on the fact that LD50 value was over 10mg/kg.The results from salmonella in vivo test and mouse micronucleus in vivo test revealed that the compounded microbial flocculant is a genetically non-toxic substance.Furthermore,compounded microbial flocculant has little effect on the growth of all the rats, and any morphologic abnormal phenomenon hasnt appeared.
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| 关 键 词： | 复合微生物絮凝剂 CMBF 废水处理 环境保护 安全评估 生物安全性 |
Security evaluation of compounded microbial flocculant |
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| MA Fang,WANG Bo,FAN Chun,YANG Ji-xian,LI Bai-xiang,LIU Yan-bin.Security evaluation of compounded microbial flocculant[J].Journal of Harbin Institute of Technology,2004,11(1):38-42. |
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| Authors: | MA Fang WANG Bo FAN Chun YANG Ji-xian LI Bai-xiang LIU Yan-bin |
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| Affiliation: | 1. School of Municipal and Environmental Engineering,Harbin Institute of Technology,Harbin 150090,China
2. Harbin Medical University,Harbin 150001,China |
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| Abstract: | A new kind of compounded microbial flocculant (CMBF) for water and wastewater treatment has been developed through biological technology. In order to discuss its biological security, four groups of experiments, rat acute toxicity test via mouth, salmonella assay in vitro, mouse micronucleus in vivo test and teratogenesis test were conducted to evaluate its general toxicity, genotoxicity and generative toxicity. The experimental results showed that this type of compounded microbial flocculant was a substantial non-toxic substance based on the fact that LD50 value was over 10 mg/kg. The results from salmonella in vivo test and mouse micronucleus in vivo test revealed that the compounded microbial flocculant is a genetically non-toxic substance. Furthermore, compounded microbial flocculant has little effect on the growth of all the rats, and any morphologic abnormal phenomenon hasn't appeared. |
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| Keywords: | compounded microbial flocculant (CMBF) generative toxicity genetic toxicity security evaluation |
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