Pilot-scale and bench-scale studies were performed to investigate the influence of aeration on hybrid PAC/UF process, in terms of pollutants removal and membrane fouling. The results showed that, compared with intermittent aeration, PAC/UF process had a better organic matter removal under continuous aeration condition. PAC could relieve the membrane fouling, and the function could be improved by the utilization of continuous aeration. Increasing aeration rate could relieve membrane fouling either. While intermittent aeration could save energy about 0221 kW·h/m3. Taking all factors into consideration, intermittent aeration was economical and reasonable for hybrid PAC/UF process.