To study the comfort of "Building-Bridge Integration" station hall structure under various dynamic loads and the applicability of the existing vibration norms, a large passenger railway station was tested under pedestrian load and transit train load, meanwhile field investigation were implemented to study crowd disturbance response under the vibration level. This paper established comfort quantitative indicators, which is suitable to evaluate the annoyance rate of "Building-Bridge Integration" structure, based on different load styles and structure spans, used the existed annoyance rate model considering the fuzziness and randomness. Results indicate that partial region vibration level is under perception value, practical annoyance rate is 2%; partial region vibration intensity exceeds 70 dB, theory annoyance rate is 50%, but practical annoyance rate is 2%, traditional comfort evaluation standard can't accurately evaluate this structure type. Annoyance rate model can quantify annoyance rate under any vibration intensity, the vibration limit is between 75-90 dB, the result based on measured data is consistent with ISO standard in vibration response description, which make up deficiency of present comfort standard about long span"Building-Bridge Integration".