To investigate the regularity of energy evolution in the process of rock loading with imperfect bounding surface, uniaxial cyclic loading and unloading compressive tests were conducted on granite with mineral bonding slope, during which its acoustic emission was detected. It concludes that: 1) The "Effective energy ratio" (defined as cumulative elastic energy / input rock total energy) can be used as a token of rock energy storage level, which can also indirectly reflect the internal structure of the rock as the stress state changes. 2) The test object's acoustic emission energy release rate at the bonding surface of the test object was higher than that at peak intensity during the loading process. Acoustic emission at the site of bond surface release was short and strong, and the duration of acoustic emission at peak intensity was long but the acoustic emission and energy release rate was lower than that at bond surface failure. 3) No acoustic emission phenomenon occurred in the unloading process with low stress level or such phenomenon could be ignored. However, when the stress reached a certain level, where the elastic energy of granite accumulation exceeded the dissipation energy of local damage, short and intense brittle failure occurred during unloading. 4) The "AE detection efficiency" (cumulative AE / cumulative dissipation energy) is defined based on the fact that AE energy is part of the dissipative energy. It was found that "AE detection efficiency" decreased during the compaction phase and increased in the elastic phase. It reached peak value when the bonding surface was partially destroyed. After that, it tended to decrease until the peak intensity of bonding surface was reached. 5) From the energy point of view, the stress level corresponding to unloading rupture is lower than the loading strength, but it should not be lower than the stress level corresponding to the elastic energy which is equal to the dissipation energy at peak intensity.