Considering the shortages of traditional methods in calculating a large-scale and complex structure with multiple-point wind excitations,the random wind-induced response analysis of large-scale and high-rise structures based on pseudo excitation method is presented.The multiple-point fluctuating wind loads are changed into harmonic pseudo-excitation vector by using the pseudo-excitation method,then the expression of wind-induced response can be derived according to the stationary stochastic theory which can automatically take the space correlation of multiple-point wind-excitations into account.The highest building under construction in Shenzhen city,Jin-Ji Tower,is employed as a numerical example.Results show that this method exhibits high accuracy and efficiency,and it is valuable in the analysis of stochastic wind-induced response of real complex and high-rise tower structures.