To analyze the effect of bicycle flow caused by curb parking on segregated bicycle lane, this paper analyzed the group and compression characteristic of bicycle flow. Then based on airflow analysis method, we put forward the model of bicycle compression wave to describe the state of cycle deceleration-following and stop under the influence of parking process of vehicles. By means of the model, the maxim queuing position is calculated when the situation caused by curb parking is the worst. Furthermore, the shortest distance between curb-parking space and upper intersection is calculated. Based on the field data measured at Dongzhongshi Road in Suzhou city, comparing the calculated results with the real stop wave rate, the average value of relative error is less than 8.57％. By controlling the interference time of bicycle and density of bicycle flow, the phenomenon that queuing bicycles extend to upper intersection can be reduced effectively, so that the traffic congestion can be relieved and the traffic hidden danger can be reduced.