To study the relationships between human thermal sensation, thermal comfort and thermal acceptability at the local parts of the body and the overall in cold radiation non-uniform environment, 20 subjects were invited to participate in three experimental conditions, overall slightly cool and overall neutral conditions with asymmetrical cold radiation, and an overall neutral uniform condition. The subjects were asked to report their thermal responses such as thermal sensation, thermal comfort, and thermal acceptability in these three conditions. An overall thermal sensation evaluation model considering local thermal sensation and a thermal acceptability evaluation model based on the maximum local thermal sensation difference were presented,which were both applied to thermal environment with non-uniform radiation from the cold exterior window and wall. The results showed that there was no significant relationship between the overall thermal acceptability and overall thermal sensation, while the overall thermal acceptability was significantly correlated to the overall thermal comfort.