To study on mechanical properties of non-metal faced sandwich panels under bending load, the force-deformation relationships of differential equations were used to derive and simplify deformation calculate formulas and bearing capacity calculate formulas of the single-span simply supported sandwich panels under uniformly distributed load and concentrated load, considering the influence of the shear deformation of core. Bending properties of two groups of sandwich panels with calcium-silicate (CS) faces and polyurethane (PU) cores were tested through vacuum chamber loading and sandbag loading and they were analyzed through the finite element methods (FEM) with software ABAQUS. Bending deflection and bending bearing capacity of sandwich panels in serviceability limit states and bearing capacity limit states are got separately and the corresponding load-displacement curves are drew. The results show that the theoretical calculation results are identical to the experimental results and FEM results. It is concluded that the simplified formulas can be used to calculate accurately bending deflection and bending bearing capacity of non-metal faced sandwich panels.