To obtain the response rules of typical super high-rise building during the whole construction process, based on Shenzhen Kingkey Financial Center, the construction monitoring system was established and improved to keep tracking the whole process of construction. Response data of the construction process was attained to verify system availability. Furthermore, the tracking simulation of full-process construction was conducted using the developed super high-rise construction simulation technology, and the law of accumulation of vertical deformation and development of stress was studied by integrating simulation data and monitoring data on Shenzhen Kingkey Financial Center during full-process construction. The results indicate that vertical compressive deformation of the structure and stress of critical vertical elements grow steadily with the progress of construction schedule, without large mutation, overall stress of components of structure is small and has much redundancy, which proved that construction plan and schedule of Shenzhen Kingkey Financial Center was reasonable. Final simulation results agreed well with the measured results certified to practicability and accuracy of full-process simulation and monitoring technology, which can be applied in the following of whole process of similar super high-rise structure and guide the construction process.