At present, study on the theory of quantify leakage is few internationally, and the establishment of water supply network leakage model is used more for estimating microscopic model but not used for calculation of whole physical leakage in water supply network. This paper modeled leakage of different consumers, different characteristics of leakage by water supply network leakage experimental platform. The theory of blind source separation was applied to leakage separation, and the data obtained from on-line monitor system was processed by fast independent component algorithm to get leakage separation. This provides powerful basis for taking measures of water supply network management, reduces leakage and improves level of controlling leakage.