In order to meet the need of concrete-filled double skin composite shear walls in construction, quasi-static testing of two concrete-filled double skin composite shear walls have been carried out, and analysis of their load bearing properties and seismic performance has been completed. The results show that the composite shear wall can give full play to both materials and is an anti-shear member with superior performance. Although opening reduces shear wall’s bearing capacity and initial stiffness, it has good influence on the shear wall’s deformation capacity and energy dissipation capacity. A large amount of numerical models have been established to analyze the influence of opening configuration parameters on the composite shear wall’s seismic behavior, including the position, the shape and the size of the opening. Based on the finite element analysis, formula for calculating the reduction coefficient of bearing capacity has been proposed, and the structure requirement of opening has been suggested and verified.