Seismic performance of the multi-ribbed composite wall structure with large space at the bottom, combined with the new oblique frame-grid used in multi-ribbed structure was studied in this paper. The pseudo-static experiment of two 1/2-scale multi-ribbed composite wall supported on frame shear-wall structure was conducted. Under the low reversed cyclic loading, the failure process and force transfer mechanism of the oblique and orthogonal frame-gird specimens was analyzed. The hysteretic characteristic of inter-story displacement, steel load-strain curves of the members, residual deformation ratio of the specimen was discussed. The results show that the structure have good seismic performance. The unique oblique frame-grid design can improve the overall ductility, deformation, collapse-resistant capacity and reparability.