To investigate the aging characteristics of the ultrafiltration membrane used in water treatment, the polyvinylidenefluoride (PVDF) ultrafiltration membrane was aged with sodium hydroxide (NaOH), sodium carbonate(Na₂CO₃), sodium hypochlorite (NaClO), hydrochloric acid (HCl) and citric acid (H₃Cit), respectively. The effect of low-concentration cleaning agents on the aging of the PVDF membrane was investigated, with the analyzing of the parameters of pure water flux, total organic carbon (TOC) rejection, tensile strength, field emission scanning electron microscopy (FESEM), contact angle and fourier transform infrared (FTIR). Experimental result shows that acid, alkali and oxidant, especially NaOH and NaClO, changed the structure and performance of the PVDF ultrafiltration membrane. After exposed to NaOH, Na₂CO₃ and NaClO for 75 days, the total organic carbon (TOC) rejection efficiencies decrease from 36% to 15%, 27% and 17%, respectively. Compared to the virgin membrane, the tensile strength and ultimate elongation of the membrane which aged 15 days with NaOH declines by 11% and 20%, respectively. The negative effect of alkali and oxidant on mechanical performance and TOC rejection was higher than that of HCl and H₃Cit, and the decreasing of hydrophilicity of the membrane exposed to NaClO is more significant than that of the other cleaning agents. The dehydrofluorination, which can generate of C＝C and C＝O bond, is one of the most important reasons that caused the ageing of PVDF membrane.