To investigate the relationship of surface energy between mineral filler and its chemical compositions, the grey correlation method and principal component analysis method were employed to quantitatively analyze the relationship model measured by capillary rise method. Results showed that measured surface energy parameters of mineral filler agreed with the value calculated on the basis of chemical composition surface energy parameters. A quantitative model related to the changing mineral filler surface energy parameter, chemical composition content and the unchanging chemical composition surface energy parameter was proposed. The surface energy of mineral filler can be determined by this model when the chemical compositions are given. All of the results can provide theoretical direction to further study on mineral filler surface energy for road engineering.