To study the influence of the variation of key parameters of the head of monopole (two-wheel type) on the wind load and its change law, wind-tunnel tests were carried out on large-scale models of the head of monopole in uniform flow field, based on the high-frequency force balance technology. The influence of monopole diameter, antenna size, overhang distance, and other parameters on the drag coefficient was analyzed, the variation of the drag coefficient in the range of high Reynolds number was studied, and the contribution of the external antenna to the overall resistance of the head of monopole was discussed. Results show that the drag coefficient of the integrated models was not sensitive to the variation of the Reynolds number, and it decreased as the monopole diameter increased. The drag coefficient was greatly affected by the wind direction angle, and the descending slope of the drag coefficient increased as the monopole diameter increased, while the downward trend gradually tended to be gentle. In this study, the ratio of the resistance of the external antenna to that of the integrated models was defined as the antenna shape influence coefficient. Test results show that the influence coefficient increased with the increase in the Reynolds number and tended to be stable in the range of high Reynolds number. As the monopole diameter increased, the influence coefficient decreased, and the contribution of the antenna to the integrated models was weakened. The antenna size had little effect on the drag coefficient and its variation trend. The drag coefficient increased as the overhang distance increased, and its variation with Reynolds number was less affected by the overhang distance.