| 引用本文: | 高崇婧,刘丽艳,马万里,刘丽华,李一凡.哈尔滨市油漆工人尿液中PAEs代谢物污染水平[J].哈尔滨工业大学学报,2016,48(2):44.DOI:10.11918/j.issn.0367-6234.2016.02.008 |
| GAO Chongjing,LIU Liyan,MA Wanli,LIU Lihua,LI Yifan.Levels of phthalate metabolites in urine of house painters in Harbin[J].Journal of Harbin Institute of Technology,2016,48(2):44.DOI:10.11918/j.issn.0367-6234.2016.02.008 |
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| 摘要: |
| 为了解油漆工人体内邻苯二甲酸酯（phthalate acid esters，PAEs）的污染特征和暴露水平，2013年在哈尔滨市采集了10个油漆工人和10个普通人群的尿液样品，分析尿液中14种PAEs代谢物的质量分数水平.结果表明，PAEs代谢物普遍存在于油漆工人和普通人群体内，油漆工人尿液中PAEs代谢物的质量分数普遍高于普通人群，邻苯二甲酸单甲酯（mMP）、邻苯二甲酸单丁酯（mBP）和邻苯二甲酸单异丁酯（miBP）为主要代谢物.不同相对分子质量PAEs代谢物的比较表明，油漆工人体内低相对分子质量代谢物的质量分数显著高于普通人群，说明油漆工人受到油漆涂料中释放的PAEs污染.所有尿液中PAEs的日暴露量均低于美国环境保护署给出的人体内PAEs最大参考暴露剂量，说明油漆工人和普通人群PAEs的暴露风险均处于安全水平.
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| 关键词: 邻苯二甲酸酯代谢物 尿液 油漆工人 普通人群 暴露评估 |
| DOI：10.11918/j.issn.0367-6234.2016.02.008 |
| 分类号:X838 |
| 文献标识码:A |
| 基金项目:国家自然科学基金项目(21277038);城市水资源与水环境国家重点实验室(哈尔滨工业大学)自主课题(2013DX14). |
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| Levels of phthalate metabolites in urine of house painters in Harbin |
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GAO Chongjing, LIU Liyan, MA Wanli, LIU Lihua, LI Yifan
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(International Joint Research Center for Persistent Toxic Pollutants (IJRC-PTS), State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology,150090 Harbin, China)
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| Abstract: |
| Phthalate acid esters (PAEs) are widely used in building materials, such as paints. In order to determine the pollution characteristics and exposure levels of PAEs to painters, 10 urine samples from painters and other 10 urine samples from general individuals were collected in Harbin, China. 14 phthalate metabolites in the urine samples were comparably analyzed. Urinary concentrations of metabolites with painters were higher than those with general population, in which the mMP, mBP and miBP are major metabolites. Furthermore, the concentrations of low molecular weight metabolites within the urine of the painters were significantly higher than those within the general individuals, indicating that painters exposed to low molecular weight PAEs during their working time. Finally, the daily intakes of PAEs were estimated, which were all lower than the reference dose by U.S. EPA, indicating that the exposure risk with PAEs for both painters and general population were in safe level.
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| Key words: phthalate metabolites urine painter general population human exposure |
